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Universal:MGCHrm
  • methylglutaconyl-CoA hydratase (reversible), mitochondrial
  • h2o_m + 3mgcoa_m ⇌ hmgcoa_m
    h2o_m:0 + 3mgcoa_m:-5 ⇌ hmgcoa_m:-5
RHEA:21536
  • (3S)-3-hydroxy-3-methylglutaryl-CoA = 3-methyl-(2E)-glutaconyl-CoA + H2O
  • View on RHEA
Properties
  • Names: (S)-3-Hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)[1,2,3,4], (S)-3-Hydroxy-3-methylglutaryl-CoA hydro-lyase[1,2,3,4], (S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase[1,2,3,4], (S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)[1,2,3,4], 3-methylglutaconyl CoA hydratase[1,2,3,4], Methylglutaconyl-CoA hydratase[1,2,3,4], methylglutaconase[1,2,3,4], methylglutaconyl coenzyme A hydratase[1,2,3,4], methylglutaconyl-CoA hydratase[1,2,3,4], METHYLGLUTACONYL-COA-HYDRATASE-RXN[3]
Data Sources: [0] 21536 via RHEA, [1] rxn01504 via ModelSEED, [2] rxn27998 via ModelSEED, [3] rxn30733 via ModelSEED, [4] rxn32471 via ModelSEED
Linkouts
Data Sources: [0] 21536 via RHEA, [1] rxn01504 via ModelSEED, [2] rxn27998 via ModelSEED, [3] rxn30733 via ModelSEED, [4] rxn32471 via ModelSEED
Reaction Participants
Stoich. BiGG ID Name Reference x [side] Compartment
1 hmgcoa_m (3S)-3-hydroxy-3-methylglutaryl-CoA(5-) CHEBI:43074 1 [L] 0
-1 h2o_m water CHEBI:15377 1 [R] 0
-1 3mgcoa_m trans-3-methylglutaconyl-CoA(5-) CHEBI:57346 1 [R] 0
In BiGGr
Organism Model
Homo sapiens RECON1
Phaeodactylum tricornutum CCAP 1055/1 iLB1027_lipid